![]() ![]() Arnie is funny, irreverent, and has an uncanny ability to take complex hard science topics and make them digestible for physicians. One of my favorite lecturers on the face of the earth is Arnie Caplan, who is arguably the discoverer of what we currently call “mesenchymal stem cells” (MSCs) (4). Find a Location The Scientific Debate Behind the Term “Stem Cell” Having said all of that, my focus here will be on the science and not on the regulatory argument.Ĩ5 clinic locations offering non-surgical Regenexx solutions for musculoskeletal pain. ![]() This has made it difficult for legit medical providers offering orthobiologic treatments as they are often the baby getting thrown out with the proverbial bathwater. The biggest offenders were clinics using demonstrably dead cell birth tissue therapies and advertising these as live stem cell therapies (19-22). On the other hand, many companies are pursuing multi-year expensive clinical trials to get the legal right to market stem cell therapy as an FDA-regulated drug.Īlso, realize that we got here to what I call the “stem cell wild west” with an FDA sensitized to this issue because of a raft of companies offering to treat every known disease with “stem cell therapy”. On the one hand, multiple court cases have determined that society benefits from doctors being free to use whatever works to help patients and to describe that in any way that helps patients conceptualize the therapy (1-3). Given that our company both has affiliate clinics that use orthobiologics and also has several orthobiologic drug candidates in front of the FDA, I can see both sides of that argument. While the recent loss by the FDA at the hands of judge Bernal in LA regarding classifying adipose stromal vascular fraction as a drug has shaken that space up a bit, reading countless FDA documents makes it clear that the agency doesn’t like companies and practitioners using this terminology to describe treatment: It’s very clear that the FDA and FTC do not like physicians using the term “stem cell therapy”. I’ll cover the concept that bone marrow concentrate contains stem cells and that our current understanding of its mechanism of action is tied to that stem cell content. Today I’ll review the pure science of whether bone marrow concentrate is a stem cell therapy. It’s also been an interesting scientific ride as well. This has been an interesting few years with regard to the regulations behind using the term “stem cell therapy”. ![]()
0 Comments
![]() ![]() The CD Archive collects thousands of Shareware and Cover CD-ROMs from the heyday of the CD-ROM (late 1980s to mid 2000s) and provides ISO images as well as links inside these collections of software. In addition to this, the project also catalogs other computing and gaming resources such as software and hardware manuals, magazine scans and computing catalogs. The goal of the TOSEC project is to maintain a database of all software and firmware images for all microcomputers, minicomputers and video game consoles. The project has identified and cataloged over 450,000 different software images/sets, consisting of over 3.60TB of software, firmware and resources. TOSEC catalogs over 200 unique computing platforms and continues to grow. The main goal of the project is to catalog and audit various kinds of software and firmware images for these systems. ![]() The Old School Emulation Center (TOSEC) is a retrocomputing initiative dedicated to the cataloging and preservation of software, firmware and resources for microcomputers, minicomputers and video game consoles. The collection includes a broad range of software related materials including shareware, freeware, video news releases about software titles, speed runs of actual software game play, previews and promos for software games, high-score and skill replays of various game genres, and the art of filmmaking with real-time computer game engines. DESCRIPTION The Internet Archive Software Collection is the largest vintage and historical software library in the world, providing instant access to millions of programs, CD-ROM images, documentation and multimedia. ![]() ![]() CALENDAR YEAR OF 1942 Schedule A Code Number 0981700 0 981 900. 3, Download Marine Aquarium Screensaver from here and install it using above serial number. Sim aquarium 3 Serial Number is helpful for three dimensional glasses and monitors supported. Sim Aquarium 3 Crack Torrent Downloads sponsored Sim Aquarium 3 Crack Crack . dream aquarium installed Open the file named Enter Serial Number then. at Sim Aquarium Premium Edition version 3 there are a few additional features and fixes bugs in the previous version, let's try and put on your Windows computer . I lost or didn't receive the SimAQUARIUM Activation Code!. Marine Aquarium 3 Screensaver Serial Number, keygen memories. Sim aquarium 3 Crack + Serial Key Full Version: Sim aquarium 3 Crack is a . from here and install it using above serial number. This key code for clownfish aquarium direct, as one of the most involved sellers. ![]() acronis true image 2016 serial number crack for idm. magix music maker 2007 deluxe no-cd crack for sims 3 bad screen crack prank on mini ipad max payne 3 activation code keygen generator autodesk. Sim Aquarium 3 Key, Activation Code, Keygen Download Sim Aquarium 3 Key, Activation Code is very beautiful . Need to enter serial number after restarting PC. For the first time, the Oklahoma Aquarium will host nine nights of indoor . ![]() up and identify NAICS Codes by Keyword or code number NAICS-to-SIC Cross. 2039 - Crack the Code 2040 - Comm Module 4dX 2041 - Back to Base-ics 2042. Wind is variable at 3 knots, 10 statute miles visibility, Ceiling is Overcast at 4,100. ![]() ![]() ![]() Avid Pro Tools HD 10.3.10 + Virtual Instruments (Mac OS X) 5. aHR0cDovL2RsZnJlZTI0aC5jb20vc29mdHdhcmUvNDAzOTk1LWF2aWQtcHJvLXRvb2xzLWhkLXYxMDMxMC1tYWMtb3MteC5odG1s. Avid Pro Tools HD v10.3.10 MacOSX-OPENSSH 2.27GB. Download our Keygen for Pro Tools Ultimate 2021 or 2020. All of these Pro Tools HD have already been cracked for windows. Lastly, this is a user community so if you would like to send in your thoughts and experiences of buying or building a Pro Tools computer than contact us with your buying a Pro Tools computer tips and tricks. In addition, you will have the option to access your projects from any device with Pro Tools. If you are looking for a list of Windows computers approved for Pro Tools then Avid, the makers of Pro Tools, have produced one a of Pro Tools windows computers as well as a list of Apple macOS computer approved for Pro Tools.īelow are some recent articles but click here for the archive of articles on what computer to use for Pro Tools. Logic Pro X, Pro Tools 10-2019, and Studio One V4 on Mac, as well as Windows. We don't sell anything either so you can be sure of impartial advice from the largest independent Pro Tools user community in the world - even better all our Pro Tools computer advice is completely free. Easily create animations with our suite of professional animation tools including a light table, onion skinning, easy flipping between cels, camera movement. It gives you whole life enjoyment of free updates and technical support. We are not tied to any particular platform so you can find open-minded advice on both Mac and Windows PC for Pro Tools. SketchUp is a premier 3D design software that truly makes 3D modeling for everyone, with a simple to learn yet robust toolset that empowers you to create. Offers a simple and intuitive interface which provides quick access to all the tools enabling the users to conveniently perform all tasks with great ease. Independent Advice On Buying A Pro Tools Computer Though Pro Tools First is suitable for beginners, there’s much more you. Pro Tools First gives you a total of 16 tracks, 4 simultaneous inputs, a massive instrument library, and access to an Audio Suite. However, in this version, the features and available tracks are quite limited. The installation is the same for both, only the iLok authorization is different. The first version of Pro Tools is free to download and use. If you are looking for advice on buying a computer for audio recording with Pro Tools then we have lots of advice from both Pro Tools professionals and Pro Tools enthusiasts about getting the best Pro Tools computer for you. Pro Tools 10.x uses a single installer for both Pro Tools and Pro Tools HD. ![]() ![]() ![]() These games can provide a great leisure time for students that like gaming.Īll genres of games have very good options for you to try out. There are many unblocked online games that students can play on their campuses. Therefore, you have got to take a leap of faith and see what is available out there. ![]() There are so many other games as well, but I can’t list all of them here in this article. Other popular games in the arcade genre are Vex 4 and Slope Ball. Tunnel Rush is a great game for adrenaline junkies looking to have a good time. You would be very pleased to know that there are some great arcade games that you can play as well. These are the oldest form of games, and many gamers still prefer then over other genres. Īrcade games have always been a favorite of many gamers. Other popular games include Soccer heads. If you are more into sports games, then Basketball Legends unblocked is a very good choice. Fireboy and Watergirl and Tank Trouble is a very fun and enjoyable game to play with your friends. Therefore, unblocked two player games are also very important. The ability to play the same with your partner or your friend is begging for a good experience. Modern Block Paint is another great game to play with multiple friends and see who has got in himself to come out on top of the leaderboard. Gun Mayhem and Rooftop Snipers are a fine example of shooting games that are very fun to play.įor gamers looking to get into the multiplayer side of things, 1vs1.LOL unblocked is a great game that tests your shooting skills by pitching you against real-life gamers. Moto X3M is one such fun bike game that you can play to have a great time.įPS or shooting games are preferred by many gamers due to their competitive nature. If you are more into bike racing, then there are games for that as well. This game has leaderboards so it can provide you a competitive gaming experience If you are after that. However, if you wany a more serious experience then the Madalin Stunt Cars 2 unblocked is a great game to play with friends. This game is all about drifting at very high speeds, which is very fun and provides good entertainment in between the different breaks you get from the schoolwork. Among the top ones I will recommend Drift Hunters unblocked. There are many racing games that you can play. that you can access anytime?įeeling excited? So, let’s dive straight into the list of games without wasting any time. So, are you ready to find out about more than 1500 free online games across all the different genres like racing, shooting, arcade, etc. Today, I will be telling you about some of the best unblocked online games that you can play without needing any special software or application. If you are wondering that then don’t worry. Are you looking for the top unblocked games 76? There are many great unblocked games you can play from the comfort of your school or other enterprises, but which one is the best? ![]() ![]() ![]() An Instapaper Text bookmarklet that converts any webpage you are reading into a minimal easy to read format.Search your entire Instapaper library (super useful).A Send To Kindle bookmarklet to send individual articles to Kindle directly.Kindle Digest limit is upped to 50 articles from 10.Instapaper’s premium subscription costs a dollar a month (billed quarterly) and it is perhaps the best dollar a month you’ll ever spend.įor less than third the cost of your frappuccino, a month, this is what you get: The Best Dollar A Month You’ll Ever Spend See an article on Facebook you want to read later on your Kindle? Right-click -> Instapaper, and at your specified time, the article will show up on your Kindle, along with other unread items of the day. But does it get any more personal than picking the articles you want to read yourself?Īnd you can do it anywhere, at any time, on any device with a web browser (including the iPhone) thanks to the bookmarklet and the browser extensions. Your Own Personalized MagazineĪpps like Flipboard like to tell you how personalized their apps are. Add a time of delivery and the time zone and you are done. You can also set it to trigger only if you have 1/3/5 unread articles in your Instapaper queue. You can have the Kindle Digest sent daily or weekly. With a free account, you can send up to 10 articles to your Kindle every day and a premium subscription ups it to 50 (more on premium subscription later). On the same page, scroll down and locate Set Automatic Delivery.Ĭheck the option that says – Send my Unread articles to my Kindle automatically. ![]() Go to your Kindle Personal Document Settings page and add the email Instapaper gives you to the Approved Personal Document E-mail List.įrom the Send-To-Kindle E-Mail Settings page, find your unique Kindle email address (if you don’t know it already), go to Instapaper’s settings page and paste it.Ĭongratulations, Instapaper and Kindle are now connected. Now, from Settings -> Manage Your Kindle, connect your Instapaper account with your Kindle. First, you need to sign up for an Instapaper account and use the bookmarklet or extension to save articles to Instapaper. Looking back at how much time I spent over the last month manually creating ebooks from articles, doing so automatically with Instapaper seems a little comic. Automatically Deliver Unread Instapaper Articles To KindleĪutomatically. Lets take this step by step, starting from the obvious and moving up to the truly awesome. I had used it when researching for read later services and settled for Read It Later (now known as Pocket), mostly because it was free while Instapaper’s mobile apps were not. Speaking of something better, one fine day I was reunited with Instapaper. But there’s always something better out there. And I even got there, using the Send To Kindle extension that sends any web page to your Kindle device and when I came across more than one article, I just manually made an ebook of them using Readlists. But, like every other techie out there, I wanted it to do more. ![]() ![]() ![]() ![]() from the list of words below to find all bible verses that include that word or name. ![]() God intended for the Israelites to travel into their new home in Canaan, but when the Children of Israel disobeyed God in Exodus 16, there were sever consequences.Because of their disobedience the Israelites would wander in the wilderness for forty years. And the LORD said to Aaron, Go into the wilderness to meet Moses. 4 Then was Jesus led up of the Spirit into the wilderness to be tempted of the devil.Ģ And when he had fasted forty days and forty nights, he was afterward an hungred.ģ And when the tempter came to him, he said, If thou be the Son of God, command that these stones be made bread.Ĥ But he answered and said, It is written, Man shall not live by bread alone, but by every word that proceedeth out of the mouth of God.ĥ Then the devil taketh him up into the holy city, and setteth him on a pinnacle of the temple,Ħ And saith unto him, If thou be the Son of God, cast thyself down: for it is written, He shall give his angels charge concerning thee: and in their hands they shall bear thee up, lest at any time thou dash thy foot against a stone.ħ Jesus said unto him, It is written again, Thou shalt not tempt the Lord thy God.Ĩ Again, the devil taketh him up into an exceeding high mountain, and sheweth him all the kingdoms of the world, and the glory of them ĩ And saith unto him, All these things will I give thee, if thou wilt fall down and worship me.ġ0 Then saith Jesus unto him, Get thee hence, Satan: for it is written, Thou shalt worship the Lord thy God, and him only shalt thou serve.ġ1 Then the devil leaveth him, and, behold, angels came and ministered unto him. After God had delivered the Children of Israel from slavery in Egypt, they met with many challenges. ![]() ![]() One solution could simply be to de-solder the flash chip and try again, but that requires additional tools (like a heat gun or de-soldering iron), which you may not already have. If you recall in part one of the series, an issue users may occasionally encounter when trying to dump an SPI flash chip is providing too much power to the device through the VCC connection, thereby subsequently forcing the flash chip to be in use by the SoC (system on a chip) and preventing us from dumping the firmware. So, you may be wondering – if we can already dump the firmware of a device through its flash chip, why would we need to access it or dump its firmware through UART instead? By accessing a device’s UART interface you will generally get presented a bash terminal of sorts to access the firmware which may allow you to traverse the filesystem and execute arbitrary commands, view web files, find 0 days in binaries, find scheduled tasks, backdoors, and understand generally how the device works. With the proper cabling and baud rate, the two devices can now communicate successfully. Once the UART communication begins, bits are read at a specific frequency called the “baud rate”, which can differ between devices by up to approximately 10% before the timing of bits becomes corrupted. The receiver and transmitter, marked RX and TX respectively, need to connect to a second respective UART device’s TX and RX in order to establish communications. UART works by communicating through two wires (a transmitter wire and a receiver wire) to talk to the microcontroller or system on a chip (basically the brains of the device) directly. UART is used for asynchronous serial communications to send and receive data from devices for purposes such as updating firmware manually, debugging tests, or interfacing with the underlying system (kind of like opening a new terminal in Ubuntu). What is UART?īefore we get into breaking a device and accessing it through its UART interface, let’s first discuss what UART is and how it’s used. ![]() We will discuss what UART is, why we would want to access a device through UART, and finally, how to identify and access an arbitrary UART interface on any device. In this post, we will review the process of accessing and dumping the firmware of a device through an alternative serial interface called UART(Universal Asynchronous Receiver-Transmitter). ![]() In the first part of my hardware hacking series, we discussed dumping firmware through the SPI flash chip. ![]() ![]() ![]() There's a lot of The Warriors in Huntdown, but there's also a lot of. Elsewhere, the simple act of crouching from a sprint sets you sliding on your knees, Vanquish style, before you push up against cover or maybe just unleash both barrels into an enemy's nether regions. Within your moveset there's some neat detail, too - if an enemy gets too close you can kick them back, tossing them in the air ready to be juggled with a stream of bullets. ![]() Like Rolling Thunder there's a heavy use of cover, be that ducking into doorways or behind crates and barrels, and the action is intense enough to ensure you're best carefully pushing forwards rather than running carefree through the mobs. There's an emphasis on the gunning over the running in Huntdown - a polite way to say its platforming can fall flat, but it's not so much an issue when the combat is so chunky and considered. Good god this thing is gorgeous, the density of its vision bringing its scuzzy streets alive. Put that down to the detail, the screen filled with the kind of incidental action and depth just not possible in the era which Huntdown's style apes. The work of small Swedish team Easy Trigger Games, Huntdown is a run and gun game cast in the mold of Contra and Rolling Thunder, with an artstyle seemingly borrowed from Bitmap Brothers in their prime: it's all muscular design and brooding shadows, and it looks frankly spectacular. ![]() Availability: Out now on PlayStation 4, Xbox One, PC, Mac and Switch.For shame, really, as I picked it up a few months later and realised Huntdown stands apart from others of its ilk, partly thanks to how it leans into all that excess while delivering a brilliantly taut action game at the same time. So pervasive is that influence, though, that it can become a bit wearying - which is my excuse for missing Huntdown first time around when it came out last May, its 80s excess getting lost in all those other similarly themed games drowning out the storefronts of the eShop and Steam. Small wonder that the era's been plundered so heavily by video games ever since - these VHS wonders are shorthand for the kind of hedonism and excess we pick up our controllers for in the first place. It's an incontrovertible truth that the recipe for the ultimate Friday night in involves a stash of cheap beer, some cheap weed and a scratchy 80s sci-fi classic where it soon becomes clear the cast and crew were indulging in much the same throughout the shoot: The Hidden with its machine gun wielding strippers, or Night of the Comet with its post-apocalyptic shopping mall shootouts. Some games provide very little challenge in this regard, but there are others that will likely have players pulling out their hair as they attempt to complete the seemingly impossible challenges being asked of them.A 2D run and gunner that's as in your face as an 80s Troma classic, Huntdown matches its excess with brilliant detail. For most though, platinum trophies serve simply as a sign that a player has done all that there is to do in a game squeezing out every possible drop of fun in the process. They serve as hard evidence of a player's mastery and can even give them bragging rights over their friends and fellow gamers in some social circles. Updated on August 21, 2022, by Tom Bowen: Trophies and Achievements are a great way to celebrate skill and perseverance in gaming. Some games are exclusive to the system, some aren’t, but they’re all going to be super challenging and they've all inspired gamers to replace their controller (and even TV sets) after coming so close but ending up so far. Buckle up for some of the most difficult platinum trophies on PS4. Still, from casual trophy dabblers, to those not interested at all, to dedicated trophy hunters, players have noticed that some games are much less willing to give up their trophies than others. ![]() ![]() Some veterinarians will suture a piece of plastic to the back of the ear to help hold the pinna straight while healing. This will cause the two sides of the ear to scar together so that there will be no “pocket” to fill up with blood in the future. The Variation would be to tack the two sides of the ear pinna together leaving an opening to drain any residual bleeding that may occur. There are variations in technique at this point, but all achieve the same purpose. The blood is drained, and the blood clots that would otherwise form scar tissue are removed. The ear pinna is shaved and prepped before an incision is made through one layer of skin over the length of the hematoma. Also, the ear canal may be flushed with antiseptic during anesthesia to facilitate a thorough cleaning before beginning topical treatments at home. This can greatly expedite a successful resolution of the infection. If an ear infection exists, the ear canal may be swabbed to send samples to a reference laboratory for culture and susceptibility testing. The pet is administered a general anesthetic after pre-surgical blood work confirms that there are no contraindications precluding surgery. The window of opportunity to surgically repair an aural hematoma is typically within a week of its occurrence. This is sometimes called a cauliflower effect, and can occlude the ear canal leading to increased risk of ear infections. Left untreated, the blood will reabsorb and form scar tissue, causing the ear pinna to shrink and deform. The hematoma will probably recur, and infection can occur if the hematoma is contaminated. Aspirating the blood with a needle and syringe can deflate the pinna, but this treatment is seldom effective. Surgical repair is usually recommended for aural hematomas. In any case, an ear infection should be ruled out as an underlying reason for a hematoma. The shorter the ear pinna, the less likely that a whipping action caused the blood vessels to rupture. ![]() Another cause of a hematoma can be a trauma such as from fight wounds, and this is the more common cause of hematomas in cats. ![]() The increased blood pressure in the vessels causes them to rupture. The pain and irritation causes the dog to shake its head violently, causing a whipping effect of the ear flap. ![]() Canine hematomas are usually associated with an ear infection. Dogs and cats can be diagnosed with an aural hematoma. Because the blood cannot escape the body, the ear pinna fills like a pillow or balloon. A hematoma of the ear flap (pinna) is caused by a ruptured vessel leaking blood between the layers of skin covering the inner and outer external portion of the ear. Hematoma simply means “blood filled mass”. ![]() |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |